Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 1.00 |
| ▸ | PLAUR | Q03405 | 6/20 | 0.80 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.69 |
| ▸ | EHMT2 | Q96KQ7 | 10/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499325 | 1.00 | PLAU (1.00) | PLAUPLAURNTRK1EHMT2GSK3B | |
| SCHEMBL12499165 | 0.92 | PLAU (0.84) | PLAUPLAURNTRK1EHMT2MAPT | |
| SCHEMBL12498973 | 0.91 | PLAU (0.83) | PLAUPLAURNTRK1EHMT2MAPT | |
| SCHEMBL17874500 | 0.90 | PLAU (0.81) | PLAUPLAURNTRK1EHMT2MAPT | |
| SCHEMBL18484962 | 0.89 | PLAU (0.80) | PLAUPLAURNTRK1EHMT2GSK3B | |
| SCHEMBL19002905 | 0.89 | PLAU (0.79) | PLAUPLAURNTRK1EHMT2GSK3B | |
| SCHEMBL12698763 | 0.87 | PLAUR (1.00) | PLAUPLAURNTRK1EHMT2GSK3B | |
| SCHEMBL19002885 | 0.86 | PLAU (0.75) | PLAUPLAURNTRK1EHMT2GSK3B | |
| SCHEMBL18485555 | 0.85 | PLAU (0.74) | PLAUPLAURNTRK1EHMT2MAPT | |
| SCHEMBL16622147 | 0.84 | NTRK1 (0.90) | PLAUPLAURNTRK1EHMT2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279288-A1 | APPLICATION OF PLANT JAZ PROTEINS AND DERIVED POLYPEPTIDES IN PREVENTION AND TREATMENT OF HUMAN AND ANIMAL TUMORS | Anyang Institution Of Sino-Cotton Industry Innovation (CN) | 2024-08-22 | — | — | US | disclosed |
| EP-4365294-A1 | APPLICATION OF PLANT JAZ PROTEINS AND DERIVED POLYPEPTIDES IN PREVENTION AND TREATMENT OF HUMAN AND ANIMAL TUMORS | Anyang Institution Of Sino-Cotton Industry Innovation (CN) | 2024-05-08 | — | — | EP | disclosed |
| WO-2022261851-A1 | APPLICATION OF PLANT JAZ PROTEINS AND DERIVED POLYPEPTIDES IN PREVENTION AND TREATMENT OF HUMAN AND ANIMAL TUMORS | 中国农业科学院棉花研究所 | 2022-12-22 | — | — | WO | disclosed |
| CN-115475234-A | Application of plant JAZ protein and derivative polypeptide in preventing and treating human and animal tumors | 中国农业科学院棉花研究所 | 2022-12-16 | — | — | CN | disclosed |