Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805159 | 0.91 | HSD17B10 (0.65) | HSD17B10IDO1TAAR1ADRA1AHTR2A | |
| SCHEMBL5252421 | 0.89 | IDO1 (0.66) | HSD17B10IDO1TAAR1ADRA1AHTR2A | |
| SCHEMBL31172821 | 0.79 | APLNR (0.66) | HSD17B10IDO1TAAR1ADRA1ACA12 | |
| SCHEMBL805138 | 0.79 | APLNR (0.66) | HSD17B10IDO1TAAR1ADRA1ACA12 | |
| SCHEMBL2949402 | 0.78 | TAAR1 (0.71) | HSD17B10TAAR1HTR2AHTR2C | |
| SCHEMBL8468532 | 0.78 | SLC6A4 (0.54) | HSD17B10IDO1TAAR1ADRA1AHTR2A | |
| SCHEMBL18557215 | 0.77 | IDO1 (0.53) | HSD17B10IDO1TAAR1ADRA1AHTR2A | |
| Ammonia Solution, Strong SCHEMBL266597 | 0.77 | APLNR (0.63) | HSD17B10IDO1TAAR1ADRA1ACA12 | |
| SCHEMBL487942 | 0.77 | HSD17B10 (0.62) | HSD17B10IDO1TAAR1ADRA1AHTR2A | |
| SCHEMBL17584863 | 0.77 | L3MBTL1 (0.44) | HSD17B10TAAR1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000224-B1 | Process for the preparation of pillar[5]quinone | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-07 | — | — | US | disclosed |