Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14307215 | 0.89 | ADORA2A (0.48) | ADORA2AADORA1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL15256056 | 0.88 | TDP1 (0.44) | ADORA2AKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14307205 | 0.88 | ALDH1A1 (0.44) | ADORA2AKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15256057 | 0.85 | ALDH1A1 (0.41) | ADORA2AADORA1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL14317959 | 0.85 | ALDH1A1 (0.44) | ADORA2AKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13071762 | 0.84 | ADORA1 (0.46) | ADORA2AADORA1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL13072021 | 0.82 | ADORA1 (0.42) | ADORA2AADORA1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL13211941 | 0.81 | ALDH1A1 (0.47) | ADORA2AKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15256052 | 0.80 | DPP4 (0.41) | ADORA2AKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15256095 | 0.80 | KDM4E (0.40) | ADORA2AADORA1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999520-B2 | Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |