SCHEMBL14307205

SCHEMBL14307205

Cc1ccccc1-c1nc(C)c(-c2ccccc2)nc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
KDM4E B2RXH2 7/20 0.44
RAB9A P51151 4/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
KMT2A Q03164 1/20 0.44
DPP4 P27487 1/20 0.44
LMNA P02545 2/20 0.44
GAA P10253 2/20 0.44
ADORA2A P29274 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.43
HPGD P15428 4/20 0.43
NPC1 O15118 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PDE10A Q9Y233 1/20 0.41
ENPP3 O14638 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15256056 0.96 TDP1 (0.44) ALDH1A1KDM4ERAB9AMEN1POLB
SCHEMBL14317959 0.96 ALDH1A1 (0.44) ALDH1A1KDM4ERAB9AMEN1POLB
SCHEMBL13211941 0.92 ALDH1A1 (0.47) ALDH1A1KDM4ERAB9AMEN1POLB
SCHEMBL15256052 0.91 DPP4 (0.41) ALDH1A1KDM4ERAB9AMEN1POLB
SCHEMBL15256057 0.91 ALDH1A1 (0.41) ALDH1A1KDM4ERAB9AMEN1POLB
SCHEMBL13072021 0.91 ADORA1 (0.42) ALDH1A1KDM4ERAB9AMEN1POLB
SCHEMBL13071762 0.89 ADORA1 (0.46) ALDH1A1KDM4ERAB9AMEN1POLB
SCHEMBL16622243 0.88 ADORA2A (0.48) ALDH1A1KDM4ERAB9AMEN1POLB
SCHEMBL15256095 0.88 KDM4E (0.40) ALDH1A1KDM4ERAB9AMEN1POLB
SCHEMBL16622278 0.87 KIF11 (0.46) MEN1KMT2ADPP4ADORA2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999520-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-04-07 US disclosed
EP-2254173-B1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LAB (JP) 2013-09-18 EP disclosed
EP-1873163-A1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-02 EP disclosed