SCHEMBL16622257

SCHEMBL16622257

Cc1ccccc1-c1ncc(-c2ccccc2-c2ccccc2)nc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATR Q13535 6/20 0.47
RAB9A P51151 3/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
KMT2A Q03164 1/20 0.42
ENPP3 O14638 1/20 0.42
ENPP1 P22413 1/20 0.42
CKS1B P61024 1/20 0.41
SKP1 P63208 1/20 0.41
SKP2 Q13309 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41
PDGFRB P09619 1/20 0.41
KDR P35968 1/20 0.41
FLT3 P36888 1/20 0.41
DPP4 P27487 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15256054 0.94 ALDH1A1 (0.45) ATRRAB9AALDH1A1KDM4EMEN1
SCHEMBL16750238 0.89 CKS1B (0.49) ATRRAB9AALDH1A1KDM4EMEN1
SCHEMBL16948795 0.88 RAB9A (0.47) ATRRAB9AALDH1A1KDM4EMEN1
SCHEMBL16622258 0.88 ATR (0.44) ATRRAB9AALDH1A1KDM4EMEN1
SCHEMBL16750251 0.87 ATR (0.54) ATRMEN1KMT2ACKS1BSKP1
SCHEMBL13072039 0.85 ATR (0.51) ATRRAB9AALDH1A1KDM4EMEN1
SCHEMBL28019522 0.85 RAB9A (0.51) ATRRAB9AALDH1A1KDM4EMEN1
SCHEMBL15256058 0.85 TDP1 (0.50) ATRRAB9AALDH1A1KDM4EMEN1
SCHEMBL16948794 0.84 RAB9A (0.44) ATRRAB9AALDH1A1KDM4EMEN1
SCHEMBL15256059 0.82 ATR (0.52) ATRRAB9AALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999520-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-04-07 US disclosed