Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14390490 | 0.90 | KCNH2 (0.48) | MAOBMAOAKCNH2CHRM1GNAI3 | |
| SCHEMBL2653777 | 0.78 | CYP1A2 (0.40) | SIGMAR1 | |
| SCHEMBL29842368 | 0.74 | MAPK1 (0.48) | MAPK1OPRK1SIGMAR1 | |
| SCHEMBL31580592 | 0.74 | MAPK1 (0.48) | MAPK1OPRK1SIGMAR1 | |
| SCHEMBL791466 | 0.74 | MAPK1 (0.48) | MAPK1OPRK1SIGMAR1 | |
| SCHEMBL6669807 | 0.74 | GNAI3 (0.51) | MAOBKCNH2HTR2AGNAI3GNAO1 | |
| SCHEMBL2660604 | 0.73 | EPHX2 (0.42) | SIGMAR1 | |
| SCHEMBL22710507 | 0.72 | NAAA (0.39) | MAPK1OPRK1 | |
| SCHEMBL23921717 | 0.71 | GNAI3 (0.62) | KCNH2GNAI3GNAO1GNAI1 | |
| SCHEMBL3012066 | 0.70 | CHRM1 (0.42) | MAOBMAOAHTR2ACHRM1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857401-A1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | Meiji Seika Pharma Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |