Urea

Urea

SCHEMBL1662263

NC(N)=O.NCCNCCN

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.67
CA6 P23280 5/20 0.67
CA7 P43166 5/20 0.67
CA9 Q16790 5/20 0.67
CA14 Q9ULX7 5/20 0.67
CA5B Q9Y2D0 5/20 0.67
MEN1 O00255 2/20 0.67
RECQL P46063 2/20 0.67
KMT2A Q03164 2/20 0.67
CA2 P00918 4/20 0.62
CA4 P22748 4/20 0.62
CA5A P35218 4/20 0.62
LMNA P02545 3/20 0.62
CA3 P07451 3/20 0.62
ALOX15 P16050 3/20 0.62
TDP1 Q9NUW8 2/20 0.62
CA1 P00915 2/20 0.62
ALDH1A1 P00352 1/20 0.62
TP53 P04637 1/20 0.62
KDM4E B2RXH2 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9487188 0.90 CA12 (0.62) CA12CA6CA7CA9CA14
Carbamic Acid SCHEMBL10380516 0.90 CA12 (0.62) CA12CA6CA7CA9CA14
Acetamide SCHEMBL11164476 0.88 CA12 (0.59) CA12CA6CA7CA9CA14
Carbamic Acid SCHEMBL1421167 0.88 CA12 (0.65) CA12CA6CA7CA9CA14
SCHEMBL6536397 0.88 CA12 (0.59) CA12CA6CA7CA9CA14
Carbamic Acid SCHEMBL9296897 0.88 CA12 (0.59) CA12CA6CA7CA9CA14
Bicarbonate SCHEMBL2443699 0.87 CA12 (0.67) CA12CA6CA7CA9CA14
SCHEMBL6536746 0.85 CA12 (0.61) CA12CA6CA7CA9CA14
SCHEMBL6536892 0.85 CA12 (0.56) CA12CA6CA7CA9CA14
Succinamide SCHEMBL6536887 0.85 CA12 (0.56) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109467696-B Preparation method of polyamide-tannin wood adhesive 西南林业大学 2021-08-31 CN claimed
CN-108713012-B Process for preparing higher ethyleneamines and ethyleneamine derivatives 阿克苏诺贝尔化学品国际有限公司 2021-07-02 CN claimed
CN-108602752-B Process for preparing higher ethyleneamines and ethyleneamine derivatives 阿克苏诺贝尔化学品国际有限公司 2021-07-02 CN claimed
CN-109467696-A A kind of preparation method of polyamide-tannin wood adhesive 西南林业大学 2019-03-15 CN claimed
CN-110997659-B Process for preparing propylene amine and propylene amine derivatives 诺力昂化学品国际有限公司 2023-09-12 CN disclosed
CN-116285827-A Single Ning Jijiao adhesive and preparation method and application thereof 浙江农林大学 2023-06-23 CN disclosed
US-11390607-B2 Process to prepare propylene amines and propylene amine derivatives NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-07-19 US disclosed
CN-109467696-B Preparation method of polyamide-tannin wood adhesive 西南林业大学 2021-08-31 CN disclosed
CN-109467696-B Preparation method of polyamide-tannin wood adhesive 西南林业大学 2021-08-31 CN disclosed
US-20200361910-A1 PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2020-11-19 US disclosed
CN-108137948-B Ionic oligomers and polymerizable compositions containing same for temporary use of water-cleavable materials 阿科玛法国公司 2020-06-23 CN disclosed
EP-3665168-A1 PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES Nouryon Chemicals International B.V. (NL) 2020-06-17 EP disclosed
CN-110997659-A Process for preparing propyleneamine and propyleneamine derivatives 诺力昂化学品国际有限公司 2020-04-10 CN disclosed
CN-109467696-A A kind of preparation method of polyamide-tannin wood adhesive 西南林业大学 2019-03-15 CN disclosed
WO-2019030197-A1 PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2019-02-14 WO disclosed
CN-108137948-A Ionic oligomerics and containing its be used for the provisional polymerisable compound of the material of water cleavable used 阿科玛法国公司 2018-06-08 CN disclosed
US-8409403-B2 Production of amino lignin and amino lignin cellulose resins and adhesives BLOUNT DAVID H (US) 2013-04-02 US disclosed
US-20110098384-A1 Production of amino lignin and amino lignin cellulose resins and adhesives BLOUNT DAVID H 2011-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361910-A1 PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES HRH3, HRH4, HRH1 CA12 4100/4885CA6 1249/4885CA7 3314/4885
US-11390607-B2 Process to prepare propylene amines and propylene amine derivatives HRH3, HRH4, HRH1 CA12 4057/4885CA6 1285/4885CA7 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.