Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.65 |
| ▸ | CA6 | P23280 | 5/20 | 0.65 |
| ▸ | CA7 | P43166 | 5/20 | 0.65 |
| ▸ | CA9 | Q16790 | 5/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | CA2 | P00918 | 4/20 | 0.65 |
| ▸ | CA4 | P22748 | 4/20 | 0.65 |
| ▸ | CA5A | P35218 | 4/20 | 0.65 |
| ▸ | CA3 | P07451 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL10380516 | 0.97 | CA12 (0.62) | CA12CA6CA7CA9CA14 | |
| Carbamic Acid SCHEMBL9296897 | 0.94 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL6058519 | 0.92 | MAOA (0.56) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL20639324 | 0.91 | CA12 (0.69) | CA12CA6CA7CA9CA14 | |
| Bicarbonate SCHEMBL10634656 | 0.91 | CA12 (0.69) | CA12CA6CA7CA9CA14 | |
| Bicarbonate SCHEMBL2443699 | 0.88 | CA12 (0.67) | CA12CA6CA7CA9CA14 | |
| Urea SCHEMBL1662263 | 0.88 | CA12 (0.67) | CA12CA6CA7CA9CA14 | |
| Carbamic Acid SCHEMBL1246708 | 0.87 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL10875300 | 0.86 | CA12 (0.61) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL159616 | 0.86 | CA12 (0.61) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374508-A1 | Compositions and Methods Targeting circ2082 for the Treatment of Cancer | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-11-23 | — | — | US | disclosed |
| EP-4229202-A1 | COMPOSITIONS AND METHODS TARGETING CIRC2082 FOR THE TREATMENT OF CANCER | The Brigham & Women's Hospital, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081693-A1 | COMPOSITIONS AND METHODS TARGETING CIRC2082 FOR THE TREATMENT OF CANCER | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-9682098-B2 | Compounds suited as nanocarriers for active agents and their use | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-06-20 | — | — | US | disclosed |
| US-20160145628-A1 | NANOCARRIER SYSTEM FOR MICRORNAS AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-05-26 | — | — | US | disclosed |
| US-20150320786-A1 | COMPOUNDS SUITED AS NANOCARRIERS FOR ACTIVE AGENTS AND THEIR USE | FREIE UNIVERSITAET BERLIN (DE) | 2015-11-12 | — | — | US | disclosed |
| US-9102595-B2 | Compounds suited as nanocarriers for active agents and their use | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2015-08-11 | — | — | US | disclosed |
| WO-2014203189-A1 | NANOCARRIER SYSTEM FOR MICRORNAS AND USES THEREOF | ROSETTA GENOMICS LTD. (IL) | 2014-12-24 | — | — | WO | disclosed |
| EP-2296707-B1 | COMPOUNDS SUITED AS NANOCARRIERS FOR ACTIVE AGENTS AND THEIR USE | FREIE UNIVERSITÄT BERLIN (DE) | 2014-11-12 | — | — | EP | disclosed |
| US-20110082090-A1 | COMPOUNDS SUITED AS NANOCARRIERS FOR ACTIVE AGENTS AND THEIR USE | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2011-04-07 | — | — | US | disclosed |
| EP-2296707-A2 | COMPOUNDS SUITED AS NANOCARRIERS FOR ACTIVE AGENTS AND THEIR USE | Freie Universität Berlin (DE) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009141170-A2 | COMPOUNDS SUITED AS NANOCARRIERS FOR ACTIVE AGENTS AND THEIR USE | FREIE UNIVERSITÄT BERLIN (DE) | 2009-11-26 | — | — | WO | disclosed |
| EP-2123304-A1 | Compounds suited as nanocarriers for active agents and their use | Freie Universität Berlin (DE) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320786-A1 | COMPOUNDS SUITED AS NANOCARRIERS FOR ACTIVE AGENTS AND THEIR USE | KIT, ABCB1, BCOR | CA12 3392/4885CA6 2407/4885CA7 2648/4885 |
| US-20110082090-A1 | COMPOUNDS SUITED AS NANOCARRIERS FOR ACTIVE AGENTS AND THEIR USE | KIT, ABCB1, BCOR | CA12 3392/4885CA6 2407/4885CA7 2648/4885 |
| US-20160145628-A1 | NANOCARRIER SYSTEM FOR MICRORNAS AND USES THEREOF | MKI67, ELAVL1, ELAVL3 | CA12 3798/4885CA6 4154/4885CA7 4452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.