Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.67 |
| ▸ | CA6 | P23280 | 5/20 | 0.67 |
| ▸ | CA7 | P43166 | 5/20 | 0.67 |
| ▸ | CA9 | Q16790 | 5/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 4/20 | 0.62 |
| ▸ | CA4 | P22748 | 4/20 | 0.62 |
| ▸ | CA5A | P35218 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | CA3 | P07451 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trientine SCHEMBL20639324 | 0.97 | CA12 (0.69) | CA12CA6CA7CA9CA14 | |
| Bicarbonate SCHEMBL10634656 | 0.97 | CA12 (0.69) | CA12CA6CA7CA9CA14 | |
| Carbamic Acid SCHEMBL10380516 | 0.90 | CA12 (0.62) | CA12CA6CA7CA9CA14 | |
| Oxalic Acid SCHEMBL27834960 | 0.90 | CA12 (0.62) | CA12CA6CA7CA9CA14 | |
| Bicarbonate SCHEMBL7190430 | 0.89 | CA12 (0.53) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL28053728 | 0.89 | CA12 (0.53) | CA12CA6CA7CA9CA14 | |
| Carbamic Acid SCHEMBL1421167 | 0.88 | CA12 (0.65) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL9100273 | 0.88 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL863599 | 0.88 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL3657736 | 0.88 | CA12 (0.59) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466916-A1 | ORGANIC AMINE SALT COMPOUND HAVING ANIONS SERVING AS CO2 DONORS AND APPLICATION OF SAME AS FOAMING AGENT | Shandong University Of Technology (CN) | 2019-04-10 | — | — | EP | claimed |
| EP-1645555-B1 | A METHOD FOR PRODUCING 4-AMINODIPHENYLAMINE | JIANGSU SINORGCHEM TECH CO LTD (CN) | 2011-09-28 | — | — | EP | claimed |
| EP-1591438-B1 | A PROCESS FOR PREPARING 4-AMINODIPHENYLAMINE | SINORGCHEM CO SHANDONG (CN) | 2007-11-21 | — | — | EP | claimed |
| US-11261153-B2 | Organic amine salt compounds having CO2-donating anions and their use as foaming agent | SHANDONG UNIVERSITY OF TECHNOLOGY (CN) | 2022-03-01 | — | — | US | disclosed |
| EP-3466916-B1 | ORGANIC AMINE SALT COMPOUND HAVING ANIONS SERVING AS CO2 DONORS AND APPLICATION OF SAME AS FOAMING AGENT | UNIV SHANDONG TECHNOLOGY (CN) | 2021-09-29 | — | — | EP | disclosed |
| CN-107312192-B | Organic alcohol amine salt compound and application thereof as foaming agent | 山东理工大学 | 2020-08-18 | — | — | CN | disclosed |
| EP-3466916-A1 | ORGANIC AMINE SALT COMPOUND HAVING ANIONS SERVING AS CO2 DONORS AND APPLICATION OF SAME AS FOAMING AGENT | Shandong University Of Technology (CN) | 2019-04-10 | — | — | EP | disclosed |
| US-20190016673-A1 | ORGANIC AMINE SALT COMPOUNDS HAVING CO2-DONATING ANIONS AND THEIR USE AS FOAMING AGENT | SHANDONG UNIVERSITY OF TECHNOLOGY (CN) | 2019-01-17 | — | — | US | disclosed |
| EP-0047736-A4 | VULCANIZATION SYSTEM FOR THIODIETHANOL-BASED ELASTOMERS. | AMERICAN CYANAMID CO (US) | 1982-07-19 | — | — | EP | disclosed |
| EP-0047736-A1 | VULCANIZATION SYSTEM FOR THIODIETHANOL-BASED ELASTOMERS | AMERICAN CYANAMID COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| WO-1981002740-A1 | VULCANIZATION SYSTEM FOR THIODIETHANOL-BASED ELASTOMERS | AMERICAN CYANAMID CO (US) | 1981-10-01 | — | — | WO | disclosed |
| US-4202963-A | Vulcanization system for thiodiethanol-based elastomers | AMERICAN CYANAMID COMPANY (US) | 1980-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11261153-B2 | Organic amine salt compounds having CO2-donating anions and their use as foaming agent | PHOSPHO1, METTL14, ALKBH3 | CA12 325/4885CA6 1066/4885CA7 110/4885 |
| US-20190016673-A1 | ORGANIC AMINE SALT COMPOUNDS HAVING CO2-DONATING ANIONS AND THEIR USE AS FOAMING AGENT | PHOSPHO1, METTL14, ALKBH3 | CA12 325/4885CA6 1066/4885CA7 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.