⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872594 | 0.77 | KDM4E (0.41) | — | |
| SCHEMBL4076540 | 0.77 | L3MBTL1 (0.42) | — | |
| SCHEMBL791511 | 0.73 | L3MBTL1 (0.44) | — | |
| SCHEMBL792476 | 0.71 | — | — | |
| SCHEMBL16814153 | 0.68 | LYN (0.35) | — | |
| SCHEMBL24054731 | 0.67 | — | — | |
| SCHEMBL9970901 | 0.67 | — | — | |
| SCHEMBL8025097 | 0.67 | — | — | |
| SCHEMBL2491280 | 0.67 | — | — | |
| SCHEMBL30044827 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265602-B1 | SUBSTITUTED DIHYDROPYRAZOLONES AS INHIBITORS OF HIF-PROLYL-4-HYDROXYLASES | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |