Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731190 | 0.89 | KMT2A (0.50) | TP53PTPN1NPC1HDAC1HDAC6 | |
| SCHEMBL16622768 | 0.85 | KDM4E (0.49) | NPC1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL3869761 | 0.82 | KDM4E (0.53) | HDAC1HDAC6KMT2AHTTALDH1A1 | |
| SCHEMBL5024307 | 0.82 | SMN1; SMN2 (0.56) | TP53NPC1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL21449080 | 0.82 | L3MBTL1 (0.39) | TP53PTPN1NPC1HDAC1HDAC6 | |
| SCHEMBL6415716 | 0.81 | EPHX2 (0.50) | HDAC1HDAC6KMT2AHTTALDH1A1 | |
| SCHEMBL202718 | 0.81 | MEN1 (0.61) | TP53NPC1KMT2AALDH1A1RAB9A | |
| SCHEMBL19215206 | 0.81 | CYP4F2 (0.47) | HDAC1HDAC6KMT2AHTTALDH1A1 | |
| SCHEMBL183463 | 0.80 | ALDH1A1 (0.59) | PTPN1KMT2AL3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL27973671 | 0.79 | KMT2A (0.69) | HDAC1HDAC6KMT2AALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857459-A1 | STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS | Kowa Company Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |