Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631028 | 0.77 | HTT (0.68) | HTTLMNAKDM4EMAPTHSD17B10 | |
| Vitamin K3H2 SCHEMBL29525544 | 0.77 | HTT (1.00) | HTTLMNAKDM4EMAPTHSD17B10 | |
| Vitamin K3H2 SCHEMBL297164 | 0.77 | HTT (1.00) | HTTLMNAKDM4EMAPTHSD17B10 | |
| SCHEMBL24195884 | 0.77 | CYP1A2 (0.42) | HTTLMNAKDM4EHSD17B10TP53 | |
| Vitamin K3H2 SCHEMBL2887680 | 0.76 | HTT (0.95) | HTTLMNAKDM4EMAPTHSD17B10 | |
| SCHEMBL353534 | 0.74 | HTT (0.63) | HTTLMNAKDM4EMAPTHSD17B10 | |
| SCHEMBL13933689 | 0.74 | HTT (0.63) | HTTLMNAKDM4EMAPTHSD17B10 | |
| SCHEMBL22810347 | 0.74 | ACHE (0.41) | HTTLMNAHSD17B10PKMCYP1A2 | |
| SCHEMBL29344185 | 0.74 | HTT (0.63) | HTTLMNAKDM4EMAPTHSD17B10 | |
| SCHEMBL24715826 | 0.74 | HTT (0.59) | HTTLMNAKDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857424-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL | Zeon Corporation (JP) | 2015-04-08 | — | — | EP | disclosed |