SCHEMBL4631028

SCHEMBL4631028

Cc1cc(O)c2ccccc2c1C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.68
LMNA P02545 1/20 0.68
KDM4E B2RXH2 3/20 0.52
MAPT P10636 3/20 0.52
HSD17B10 Q99714 2/20 0.52
GAA P10253 2/20 0.52
TP53 P04637 1/20 0.52
TRPM4 Q8TD43 1/20 0.48
IDO1 P14902 2/20 0.48
MEN1 O00255 1/20 0.44
NSD2 O96028 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44
MCL1 Q07820 1/20 0.44
CYP1A2 P05177 3/20 0.43
CYP2A6 P11509 1/20 0.43
TSHR P16473 1/20 0.43
EP300 Q09472 1/20 0.42
PKM P14618 2/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13851151 0.83 HTT (0.64) HTTLMNAKDM4EMAPTHSD17B10
SCHEMBL29771838 0.83 HTT (0.64) HTTLMNAKDM4EMAPTHSD17B10
SCHEMBL5185496 0.81 HTT (0.61) HTTLMNAKDM4EMAPTHSD17B10
Vitamin K3H2 SCHEMBL29525544 0.81 HTT (1.00) HTTLMNAKDM4EMAPTHSD17B10
Vitamin K3H2 SCHEMBL297164 0.81 HTT (1.00) HTTLMNAKDM4EMAPTHSD17B10
Vitamin K3H2 SCHEMBL2887680 0.79 HTT (0.95) HTTLMNAKDM4EMAPTHSD17B10
SCHEMBL353534 0.77 HTT (0.63) HTTLMNAKDM4EMAPTHSD17B10
SCHEMBL13933689 0.77 HTT (0.63) HTTLMNAKDM4EMAPTHSD17B10
SCHEMBL29344185 0.77 HTT (0.63) HTTLMNAKDM4EMAPTHSD17B10
SCHEMBL16622867 0.77 HTT (0.63) HTTLMNAKDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP claimed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP claimed
US-9284323-B2 Naphthalene acetic acid derivatives against HIV infection GILEAD SCIENCES, INC. (US) 2016-03-15 US disclosed
US-9284323-B2 Naphthalene acetic acid derivatives against HIV infection GILEAD SCIENCES, INC. (US) 2016-03-15 US disclosed
US-20150111891-A1 NAPHTHALENE ACETIC ACID DERIVATIVES AGAINST HIV INFECTION GILEAD SCIENCES, INC. (US) 2015-04-23 US disclosed
US-20150111891-A1 NAPHTHALENE ACETIC ACID DERIVATIVES AGAINST HIV INFECTION GILEAD SCIENCES, INC. (US) 2015-04-23 US disclosed
US-20150111891-A1 NAPHTHALENE ACETIC ACID DERIVATIVES AGAINST HIV INFECTION GILEAD SCIENCES, INC. (US) 2015-04-23 US disclosed
WO-2013103738-A1 NAPTHALENE ACETIC ACID DERIVATIVES AGAINST HIV INFECTION GILEAD SCIENCES, INC. (US) 2013-07-11 WO disclosed
WO-2013103738-A1 NAPTHALENE ACETIC ACID DERIVATIVES AGAINST HIV INFECTION GILEAD SCIENCES, INC. (US) 2013-07-11 WO disclosed
EP-1972351-B1 Method for inactivation of microorganisms using photosensitizers CARIDIANBCT BIOTECHNOLOGIES LLC (US) 2011-05-11 EP disclosed
CN-101412775-B Catalyst precursor for polymerization of propylene or combined polymerization, and preparation thereof BEIJING JINDINGKE CHEMICAL TECHNOLOGY CO LTD 2010-12-22 CN disclosed
EP-0332455-B1 Photosensitive material and image forming method CANON KK (JP) 1996-06-05 EP disclosed
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP disclosed
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 EP disclosed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed
US-5260164-A Silver halide, organic silver salt, cyclic reducing agent, the above compounds adapted to provide imagewise oxidized product of reducing agent upon imagewise exposure and heat development, polymer precursor, photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1993-11-09 US disclosed
US-5064744-A Heat, photopolymerization, silver halide contrast CANON KABUSHIKI KAISHA (JP) 1991-11-12 US disclosed
US-5041369-A Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye CANON KABUSHIKI KAISHA (JP) 1991-08-20 US disclosed
EP-0332455-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150111891-A1 NAPHTHALENE ACETIC ACID DERIVATIVES AGAINST HIV INFECTION NFATC1, ACIN1, NAAA HTT 1606/4885LMNA 2505/4885KDM4E 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.