Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316273 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL16622934 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL436938 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL6026483 | 0.72 | KMT2A (0.47) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL12205471 | 0.72 | SIGMAR1 (0.46) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL9801499 | 0.71 | KMT2A (0.50) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL4656852 | 0.71 | KMT2A (0.46) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL6110482 | 0.71 | CHRM2 (0.44) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL11312006 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL6026163 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2923703-A1 | TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | Abraxis BioScience, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| EP-2425840-B1 | Triazine derivatives and their therapeutical applications | ABRAXIS BIOSCIENCE INC (US) | 2015-04-08 | — | — | EP | disclosed |