Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11886594 | 0.85 | MAOB (0.71) | MAOBMAOANPC1RAB9ACASP3 | |
| SCHEMBL122581 | 0.83 | ALDH1A1 (0.60) | MAOBMAOANPC1RAB9ACASP3 | |
| SCHEMBL123187 | 0.82 | MAOB (0.68) | MAOBMAOANPC1RAB9ACASP3 | |
| SCHEMBL22668940 | 0.79 | NPC1 (0.57) | MAOBMAOANPC1RAB9ACASP3 | |
| SCHEMBL120325 | 0.75 | MAOB (0.77) | MAOBMAOANPC1RAB9ACASP3 | |
| SCHEMBL29382160 | 0.74 | MAOB (1.00) | MAOBMAOANPC1RAB9ACASP3 | |
| SCHEMBL107774 | 0.74 | MAOB (1.00) | MAOBMAOANPC1RAB9ACASP3 | |
| SCHEMBL16623269 | 0.74 | ALDH1A1 (0.42) | MAOBMAOANPC1RAB9ACASP3 | |
| SCHEMBL16334580 | 0.72 | NPC1 (0.83) | MAOBMAOANPC1RAB9ACASP3 | |
| SCHEMBL121373 | 0.72 | NPC1 (0.67) | MAOBNPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857018-A1 | Treatment or prophylaxis of proliferative conditions | University Court of The University of Dundee (GB) | 2015-04-08 | — | — | EP | disclosed |