Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | IGLV6-57 | P01721 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | GLA | P06280 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119317 | 0.81 | NPC1 (0.60) | ALDH1A1HPGDGLAHSD17B10NPC1 | |
| SCHEMBL16623286 | 0.74 | MAOB (0.56) | ALDH1A1HPGDHSD17B10L3MBTL1NPC1 | |
| SCHEMBL16623290 | 0.72 | KMT2A (0.46) | ALDH1A1IGLV6-57HPGDGLAHSD17B10 | |
| SCHEMBL10337820 | 0.63 | ALDH1A1 (0.68) | ALDH1A1IGLV6-57HPGDGLAHSD17B10 | |
| SCHEMBL16344294 | 0.63 | ACHE (0.51) | ALDH1A1IGLV6-57HPGDGLAHSD17B10 | |
| SCHEMBL31679665 | 0.63 | NPC1 (0.67) | ALDH1A1HPGDGLAHSD17B10NPC1 | |
| SCHEMBL121373 | 0.63 | NPC1 (0.67) | ALDH1A1HPGDGLAHSD17B10NPC1 | |
| SCHEMBL4696349 | 0.63 | IGLV6-57 (0.56) | ALDH1A1IGLV6-57HPGDGLAHSD17B10 | |
| SCHEMBL3834472 | 0.63 | IGLV6-57 (0.67) | ALDH1A1IGLV6-57HPGDGLAHSD17B10 | |
| SCHEMBL29349950 | 0.63 | IGLV6-57 (0.67) | ALDH1A1IGLV6-57HPGDGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857018-A1 | Treatment or prophylaxis of proliferative conditions | University Court of The University of Dundee (GB) | 2015-04-08 | — | — | EP | disclosed |