Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121022 | 0.78 | RAB9A (0.61) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL119583 | 0.78 | ALDH1A1 (0.61) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL119317 | 0.78 | NPC1 (0.60) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL121373 | 0.76 | NPC1 (0.67) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL120086 | 0.76 | ALDH1A1 (0.67) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL31679665 | 0.76 | NPC1 (0.67) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL120736 | 0.76 | ALDH1A1 (0.67) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL12987100 | 0.76 | ALDH1A1 (1.00) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL11888139 | 0.74 | KDM4E (0.74) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL26499781 | 0.74 | KDM4E (0.73) | NPC1RAB9AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857018-A1 | Treatment or prophylaxis of proliferative conditions | University Court of The University of Dundee (GB) | 2015-04-08 | — | — | EP | disclosed |