Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444812 | 1.00 | TET2 (0.39) | TET2TSHRHSD17B10MGAMGAA | |
| SCHEMBL12451759 | 0.83 | MGAM (0.41) | TET2TSHRHSD17B10MGAMGAA | |
| SCHEMBL17398486 | 0.83 | EGLN1 (0.39) | TET2TSHRZDHHC7ALDH1A1TGFBR1 | |
| SCHEMBL27848612 | 0.83 | TSHR (0.39) | TET2TSHRHSD17B10MGAMGAA | |
| SCHEMBL15110273 | 0.77 | ALDH1A1 (0.41) | TET2TSHRZDHHC7ALDH1A1TGFBR1 | |
| SCHEMBL8899182 | 0.77 | TSHR (0.44) | TET2TSHRHSD17B10MGAMGAA | |
| SCHEMBL11274143 | 0.77 | ZDHHC7 (0.48) | TET2TSHRHSD17B10MGAMGAA | |
| SCHEMBL1413253 | 0.77 | MGAM (0.44) | TET2TSHRHSD17B10MGAMGAA | |
| SCHEMBL3249891 | 0.77 | TSHR (0.44) | TET2TSHRHSD17B10MGAMGAA | |
| SCHEMBL12820309 | 0.77 | TSHR (0.42) | TET2TSHRHSD17B10MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480549-B1 | Fused imidazo[3,2-d]pyrazines as PI3 kinase inhibitors | FUNDACIÓN CT NAC DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (ES) | 2015-04-08 | — | — | EP | disclosed |