Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16726667 | 0.80 | HPGD (0.31) | HPGDHTT | |
| SCHEMBL16726671 | 0.78 | HPGD (0.34) | HPGDHTT | |
| SCHEMBL16623551 | 0.78 | JAK1 (0.34) | — | |
| SCHEMBL16623474 | 0.77 | HSP90AA1 (0.35) | — | |
| SCHEMBL17849195 | 0.77 | HSP90AA1 (0.35) | — | |
| SCHEMBL16623491 | 0.77 | JAK1 (0.34) | — | |
| SCHEMBL16623536 | 0.77 | HSP90AA1 (0.35) | — | |
| SCHEMBL16726647 | 0.77 | — | — | |
| SCHEMBL16623472 | 0.76 | JAK1 (0.33) | — | |
| SCHEMBL16623510 | 0.76 | JAK1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857400-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |