Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 9/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | SRC | P12931 | 4/20 | 0.34 |
| ▸ | ABL2 | P42684 | 4/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610742 | 0.88 | XDH (0.37) | BTKXDHABL1EGFRSRC | |
| SCHEMBL16610623 | 0.87 | BTK (0.38) | BTKXDHKDM1AABL1EGFR | |
| SCHEMBL16610802 | 0.84 | SRC (0.41) | BTKXDHABL1EGFRSRC | |
| SCHEMBL16611255 | 0.83 | CHUK (0.40) | BTKXDHABL1EGFRSRC | |
| SCHEMBL16610956 | 0.82 | BTK (0.40) | BTKXDHABL1EGFRSRC | |
| SCHEMBL16610841 | 0.81 | BTK (0.43) | BTKABL1EGFRSRCABL2 | |
| SCHEMBL16610932 | 0.80 | BRD9 (0.36) | BTKXDHABL1EGFRSRC | |
| SCHEMBL16611087 | 0.79 | CDK2 (0.40) | BTKXDHKDM1AABL1EGFR | |
| SCHEMBL16611028 | 0.79 | LRRK2 (0.42) | BTKXDHLRRK2 | |
| SCHEMBL16611838 | 0.79 | TDP2 (0.37) | BTKXDHKDM1AABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857400-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |