Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.41 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624008 | 0.87 | SLC6A2 (0.45) | SLC6A2SLC6A3SLC6A4OPRM1HTR2A | |
| SCHEMBL16624024 | 0.84 | SLC6A4 (0.48) | SLC6A2SLC6A3SLC6A4OPRM1HTR2A | |
| SCHEMBL16624303 | 0.82 | SLC6A2 (0.62) | SLC6A2SLC6A3SLC6A4KYAT1KYAT3 | |
| SCHEMBL18033525 | 0.80 | SLC6A2 (0.42) | SLC6A2SLC6A3SLC6A4AADATHTR2A | |
| SCHEMBL12367363 | 0.76 | DRD1 (0.47) | DRD2DRD3HTR2AHTR2C | |
| SCHEMBL16624030 | 0.75 | SLC6A4 (0.48) | SLC6A2SLC6A3SLC6A4KDM2B | |
| SCHEMBL2504575 | 0.71 | CYP2D6 (0.46) | SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL22523801 | 0.71 | MAPK3 (0.43) | SLC6A2SLC6A3SLC6A4OPRM1DRD2 | |
| SCHEMBL27452944 | 0.71 | MAPK3 (0.43) | SLC6A2SLC6A3SLC6A4OPRM1DRD2 | |
| SCHEMBL26768689 | 0.71 | METAP1 (0.44) | DRD2DRD3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053917-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Nissan Chemical Industries, Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015050212-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | 日産化学工業株式会社 | 2015-04-09 | — | — | WO | disclosed |