Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624007 | 0.87 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3OPRM1HTR2A | |
| SCHEMBL16624024 | 0.83 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3ACACBOPRM1 | |
| SCHEMBL18034954 | 0.81 | SLC6A4 (0.62) | SLC6A2SLC6A4SLC6A3OPRM1SIGMAR1 | |
| SCHEMBL18033527 | 0.81 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3ACACBHTR2A | |
| SCHEMBL12367363 | 0.75 | DRD1 (0.47) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL16624030 | 0.74 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3KDM2B | |
| SCHEMBL16624090 | 0.71 | ACACB (0.43) | ACACBALDH1A1 | |
| SCHEMBL26768689 | 0.70 | METAP1 (0.44) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL13521646 | 0.70 | DRD1 (0.57) | — | |
| SCHEMBL29557542 | 0.70 | DRD1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053917-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Nissan Chemical Industries, Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015050212-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | 日産化学工業株式会社 | 2015-04-09 | — | — | WO | disclosed |