Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624024 | 0.89 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3HRH3KDM2B | |
| SCHEMBL18034964 | 0.82 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3HRH3GRIN2B | |
| SCHEMBL18033538 | 0.81 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3KIF11 | |
| SCHEMBL18253962 | 0.79 | CHRNB2 (0.37) | SLC6A4SLC6A2SLC6A3HRH3KIF11 | |
| SCHEMBL16624052 | 0.78 | MTNR1B (0.46) | HRH3GRIN2BGRIN1KDM2B | |
| SCHEMBL11794884 | 0.77 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3HRH3KIF11 | |
| Hydrochloric Acid SCHEMBL11794735 | 0.76 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HRH3KIF11 | |
| SCHEMBL18252814 | 0.76 | KCNH2 (0.43) | KIF11 | |
| SCHEMBL18252817 | 0.76 | KCNH2 (0.43) | KIF11 | |
| SCHEMBL18252841 | 0.76 | KCNH2 (0.43) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053917-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Nissan Chemical Industries, Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015050212-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | 日産化学工業株式会社 | 2015-04-09 | — | — | WO | disclosed |