SCHEMBL1662450

SCHEMBL1662450

Clc1cccc(-c2ccccc2)n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
RAB9A P51151 2/20 0.68
ASIC3 Q9UHC3 1/20 0.56
ALDH1A1 P00352 4/20 0.52
HPGD P15428 4/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 3/20 0.48
HSP90AA1 P07900 2/20 0.48
HSP90AB1 P08238 1/20 0.48
JAK2 O60674 1/20 0.45
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SMO Q99835 1/20 0.42
CNR1 P21554 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ADORA2A P29274 2/20 0.42
AURKA O14965 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28214266 0.90 MEN1 (0.56) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL21295603 0.90 MEN1 (0.56) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL21295669 0.88 MEN1 (0.54) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL31008541 0.82 RAB9A (0.47) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL1071454 0.82 CYP3A4 (0.50) MEN1KMT2ARAB9AALDH1A1L3MBTL1
SCHEMBL30492599 0.82 CYP3A4 (0.50) MEN1KMT2ARAB9AALDH1A1L3MBTL1
SCHEMBL58442 0.82 MEN1 (1.00) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL24253527 0.80 JAK2 (0.45) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL38663516 0.80 CNR2 (0.50) ALDH1A1KDM4EJAK2
SCHEMBL1636596 0.80 MEN1 (0.52) MEN1KMT2ARAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903588-B Five-membered and six-membered compound, intermediate, preparation method, composition and application 厦门市博瑞来医药科技有限公司 2025-03-21 CN disclosed
CN-116903588-A Five-membered and six-membered compound, intermediate, preparation method, composition and application 厦门市博瑞来医药科技有限公司 2023-10-20 CN disclosed
WO-2021112478-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-06-10 WO disclosed
CN-107793377-B Full-color ultralong organic phosphorescent material and preparation method and application thereof 南京工业大学 2021-06-08 CN disclosed
CN-107793377-A Full-color ultralong organic phosphorescent material and preparation method and application thereof 南京工业大学 2018-03-13 CN disclosed
US-9899612-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-20 US disclosed
US-9899612-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-20 US disclosed
US-9899612-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-20 US disclosed
CN-105198875-B A kind of new aromatic amine compound and its preparation and application 吉林奥来德光电材料股份有限公司 2017-07-04 CN disclosed
US-9636375-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2017-05-02 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4824846-A FUNGICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-25 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0237963-A2 2-Azolylmethyl-2-aryl-1,3-dioxolanes and their salts, processes for their preparation, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-23 EP disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed