Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627143 | 0.92 | FFAR1 (0.41) | FFAR1PPARDBCL2ANO1PTGER4 | |
| SCHEMBL17954313 | 0.91 | FFAR1 (0.44) | FFAR1PPARDBCL2ANO1PTGER4 | |
| SCHEMBL16624620 | 0.86 | FFAR1 (0.48) | FFAR1PPARDBCL2ANO1PTGER4 | |
| SCHEMBL16624618 | 0.84 | FFAR1 (0.48) | FFAR1PPARDBCL2ANO1FFAR4 | |
| SCHEMBL16631068 | 0.83 | MAOB (0.47) | FFAR1PPARDANO1TP53PKM | |
| SCHEMBL16624623 | 0.80 | FFAR1 (0.52) | FFAR1PPARDBCL2ANO1PTGER4 | |
| SCHEMBL16627142 | 0.80 | FFAR1 (0.47) | FFAR1PPARDBCL2ANO1FFAR4 | |
| SCHEMBL16624846 | 0.79 | BACE1 (0.42) | FFAR1PPARDBCL2ANO1RAB9A | |
| SCHEMBL16624842 | 0.79 | RAB9A (0.46) | FFAR1PPARDBCL2FFAR4AKR1B1 | |
| SCHEMBL17954312 | 0.78 | FFAR1 (0.48) | FFAR1PPARDBCL2ANO1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050871-A2 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015051366-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |