Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17954312 | 0.90 | FFAR1 (0.48) | MAOBFFAR1PPARDANO1MRGPRX4 | |
| SCHEMBL16624805 | 0.88 | ACSS2 (0.42) | MAOBFFAR1PPARDBCHETP53 | |
| SCHEMBL16618237 | 0.86 | MAOB (0.47) | MAOBFFAR1PPARDANO1MRGPRX4 | |
| SCHEMBL16624618 | 0.84 | FFAR1 (0.48) | FFAR1PPARDANO1MRGPRX4NR4A2 | |
| SCHEMBL16624844 | 0.83 | FFAR1 (0.48) | FFAR1PPARDANO1MRGPRX4NR4A2 | |
| SCHEMBL16624622 | 0.83 | FFAR1 (0.45) | FFAR1PPARDANO1MRGPRX4TP53 | |
| SCHEMBL16627141 | 0.81 | FFAR1 (0.45) | MAOBFFAR1PPARDANO1MRGPRX4 | |
| SCHEMBL20101406 | 0.81 | FFAR1 (0.41) | MAOBFFAR1PPARDBCHESMN1; SMN2 | |
| SCHEMBL17954297 | 0.80 | FYN (0.43) | MAOBFFAR1PPARDMRGPRX4BCHE | |
| SCHEMBL18102828 | 0.79 | MRGPRX4 (0.62) | MAOBFFAR1PPARDMRGPRX4NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051045-A2 | 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |