Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836945 | 0.86 | MAPT (0.53) | NPC1RAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL9400487 | 0.76 | NPC1 (0.63) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23346314 | 0.76 | UQCRB (0.53) | CYP1A2MEN1KMT2AMAPTHTT | |
| SCHEMBL12169252 | 0.75 | KMT2A (0.52) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL13715754 | 0.75 | ENPP2 (0.41) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2618313 | 0.72 | NPC1 (0.51) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13619048 | 0.72 | NQO2 (0.47) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL3281028 | 0.72 | MEN1 (0.49) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30170885 | 0.72 | MEN1 (0.49) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31222685 | 0.72 | MEN1 (0.49) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193870-B2 | Fibre-reactive dyes, their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2015-11-24 | — | — | US | disclosed |
| US-20150096131-A1 | Fibre-Reactive Dyes, Their Preparation and Their Use | HUNTSMAN INTERNATIONAL LLC | 2015-04-09 | — | — | US | disclosed |