Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624717 | 0.89 | ROCK2 (0.35) | ROCK2ROCK1 | |
| SCHEMBL16627087 | 0.86 | ROCK2 (0.35) | ROCK2ROCK1 | |
| SCHEMBL16624702 | 0.85 | ROCK2 (0.46) | ROCK2ROCK1MRGPRX4 | |
| SCHEMBL16624715 | 0.78 | ROCK2 (0.46) | ROCK2ROCK1MRGPRX4 | |
| SCHEMBL18165313 | 0.76 | SMPD1 (0.43) | ROCK2ROCK1MRGPRX4 | |
| SCHEMBL16624706 | 0.76 | ROCK2 (0.48) | ROCK2ROCK1 | |
| SCHEMBL22540469 | 0.76 | ROCK2 (0.35) | ROCK2ROCK1 | |
| SCHEMBL16624701 | 0.72 | ROCK2 (0.38) | ROCK2ROCK1 | |
| SCHEMBL16624806 | 0.71 | ROCK2 (0.38) | ROCK2ROCK1 | |
| SCHEMBL16624700 | 0.68 | ROCK2 (0.41) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050871-A2 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015051366-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |