Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870951 | 0.84 | SLC22A6 (0.36) | SMN1; SMN2SLC22A6CACNA2D1CACNB3CACNA1C | |
| SCHEMBL16624811 | 0.82 | TSHR (0.40) | SMN1; SMN2KMT2ACA14MMECA12 | |
| SCHEMBL16624810 | 0.82 | TSHR (0.40) | SMN1; SMN2KMT2ACA14MMECA12 | |
| SCHEMBL15392189 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ACA14SLC22A6MME | |
| SCHEMBL15392191 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ACA14SLC22A6MME | |
| SCHEMBL1300984 | 0.80 | SLC22A6 (0.39) | SMN1; SMN2KMT2ACA14SLC22A6MME | |
| SCHEMBL10714698 | 0.80 | ABCB1 (0.39) | SMN1; SMN2KMT2ACA14SLC22A6MME | |
| SCHEMBL15493414 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2KMT2ACA14MME | |
| SCHEMBL8472485 | 0.78 | TDP1 (0.52) | SMN1; SMN2KMT2ACA14SLC22A6MME | |
| SCHEMBL7344231 | 0.78 | BHMT (0.37) | SMN1; SMN2KMT2ACA14MMECACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309204-B2 | Process for making hydroxylated cyclopentylpyrimidine compounds | ARRAY BIOPHARMA INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150099881-A1 | PROCESS FOR MAKING HYDROXYLATED CYCLOPENTYLPYRIMIDINE COMPOUNDS | GENETECH, INC. (US) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099881-A1 | PROCESS FOR MAKING HYDROXYLATED CYCLOPENTYLPYRIMIDINE COMPOUNDS | PIK3CA, DHPS, PIK3CD | SMN1; SMN2 3946/4885KMT2A 2511/4885CA14 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.