Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 16/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PNP | P00491 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15545141 | 0.87 | HPRT1 (0.81) | HPRT1POLBPNP | |
| SCHEMBL16625400 | 0.82 | HPRT1 (0.79) | HPRT1 | |
| SCHEMBL28030184 | 0.77 | POLB (0.56) | HPRT1POLBPNP | |
| SCHEMBL12354842 | 0.77 | PNP (0.68) | HPRT1POLBPNP | |
| Gs-438 SCHEMBL64567 | 0.77 | POLB (0.80) | HPRT1POLBPNP | |
| SCHEMBL23859843 | 0.77 | HPRT1 (1.00) | HPRT1PNP | |
| SCHEMBL2734697 | 0.75 | POLB (0.77) | HPRT1POLBPNP | |
| SCHEMBL12786344 | 0.74 | PNP (0.77) | HPRT1PNP | |
| SCHEMBL17232083 | 0.74 | PNP (0.58) | HPRT1POLBPNP | |
| SCHEMBL9055784 | 0.73 | POLB (0.81) | HPRT1POLBPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200020-B2 | 6-oxopurine phosphoribosyltransferase inhibitors | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-12-01 | — | — | US | disclosed |
| US-20150099722-A1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099722-A1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | HPRT1, APRT, TPMT | HPRT1 1/4885POLB 436/4885PNP 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.