SCHEMBL15545141

SCHEMBL15545141

Nc1nc2c(ncn2CCOCCP(=O)(O)O)c(=O)[nH]1

nearest known ligand 0.81

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 13/20 0.81
PNP P00491 6/20 0.72
POLB P06746 2/20 0.72
POLA1 P09884 1/20 0.69
POLG P54098 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gs-438 SCHEMBL64567 0.90 POLB (0.80) HPRT1PNPPOLBPOLA1POLG
SCHEMBL23859843 0.90 HPRT1 (1.00) HPRT1PNPPOLG
SCHEMBL16625352 0.87 HPRT1 (0.64) HPRT1PNPPOLB
SCHEMBL2346358 0.87 PNP (0.79) HPRT1PNPPOLBPOLA1POLG
Gs-438 SCHEMBL3497651 0.86 POLB (0.84) HPRT1PNPPOLBPOLA1POLG
SCHEMBL2734697 0.85 POLB (0.77) HPRT1PNPPOLBPOLA1POLG
SCHEMBL10430808 0.84 PNP (0.71) HPRT1PNPPOLBPOLA1POLG
SCHEMBL9515948 0.84 PNP (1.00) HPRT1PNP
SCHEMBL9055784 0.84 POLB (0.81) HPRT1PNPPOLBPOLA1POLG
SCHEMBL24721833 0.84 POLB (0.74) HPRT1PNPPOLBPOLA1POLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731699-A1 POLYMER The Texas A&M University System (US) 2026-04-29 EP claimed
US-12472304-B2 Adaptive neuro-fuzzy inference system for closed loop total intravenous anesthesia management SMARTTIVA INC (US) 2025-11-18 US claimed
US-20250319253-A1 Adaptive Neuro-Fuzzy Inference System for closed loop Total Intravenous Anesthesia Management SMARTTIVA INC (US) 2025-10-16 US claimed
US-20250002646-A1 POLYMER THE TEXAS A&M UNIVERSITY SYSTEM (US) 2025-01-02 US claimed
WO-2024263862-A1 POLYMER THE TEXAS A&M UNIVERSITY SYSTEM (US) 2024-12-26 WO claimed
CN-118834265-A Polypeptide with complement inhibition activity, fusion protein and medical application thereof 北京拓界生物医药科技有限公司 2024-10-25 CN claimed
CN-118266873-A Anesthesia state detection method, anesthesia state detection system, storage medium and anesthesia state detection equipment 上海岩思类脑人工智能研究院有限公司 2024-07-02 CN claimed
CN-112435741-B Sleep-aiding system using sleep latency database 杭州云睡吧健康管理有限公司 2022-07-01 CN claimed
CN-113951896-A Brain-computer interface decoding method based on intracranial brain electricity and scalp brain electricity fusion 之江实验室 2022-01-21 CN claimed
EP-4731699-A1 POLYMER The Texas A&M University System (US) 2026-04-29 EP disclosed
US-20250352656-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS PEPTOMER THERAPEUTICS PRIVATE LTD (IN) 2025-11-20 US disclosed
US-12472304-B2 Adaptive neuro-fuzzy inference system for closed loop total intravenous anesthesia management SMARTTIVA INC (US) 2025-11-18 US disclosed
US-20250319253-A1 Adaptive Neuro-Fuzzy Inference System for closed loop Total Intravenous Anesthesia Management SMARTTIVA INC (US) 2025-10-16 US disclosed
EP-4525827-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS Peptomer Therapeutics Private Limited (IN) 2025-03-26 EP disclosed
EP-2847201-B1 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS UNIV QUEENSLAND (AU) 2017-08-16 EP disclosed
WO-2017100849-A1 6-OXOPURINE PHOSPHORIBOSYL TRANSFERASE INHIBITORS THE UNIVERSITY OF QUEENSLAND (AU) 2017-06-22 WO disclosed
US-9200020-B2 6-oxopurine phosphoribosyltransferase inhibitors THE UNIVERSITY OF QUEENSLAND (AU) 2015-12-01 US disclosed
US-20150099722-A1 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS THE UNIVERSITY OF QUEENSLAND (AU) 2015-04-09 US disclosed
EP-2847201-A2 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS The University of Queensland (AU) 2015-03-18 EP disclosed
WO-2013166545-A2 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS THE UNIVERSITY OF QUEENSLAND (AU) 2013-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250352656-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS NOD2, NGLY1, CGAS HPRT1 818/4885PNP 1227/4885POLB 3084/4885
US-20150099722-A1 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS HPRT1, APRT, TPMT HPRT1 1/4885PNP 11/4885POLB 436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.