Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | POLG | P54098 | 1/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 10/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | PNP | P00491 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16020718 | 0.86 | POLB (0.49) | POLBPOLA1POLGHPRT1FGFR1 | |
| SCHEMBL16037195 | 0.85 | HPRT1 (0.52) | POLBPOLA1POLGHPRT1FGFR1 | |
| Gs-438 SCHEMBL64567 | 0.81 | POLB (0.80) | POLBPOLA1POLGHPRT1PNP | |
| Gs-438 SCHEMBL3497651 | 0.78 | POLB (0.84) | POLBPOLA1POLGHPRT1PNP | |
| SCHEMBL8720385 | 0.77 | MEN1 (0.61) | POLBPOLA1POLGHPRT1SLC22A6 | |
| SCHEMBL16625352 | 0.77 | HPRT1 (0.64) | POLBHPRT1PNP | |
| SCHEMBL8422749 | 0.75 | HPRT1 (0.70) | HPRT1FGFR1SLC22A6PNP | |
| SCHEMBL8905164 | 0.75 | HPRT1 (0.72) | POLBPOLA1POLGHPRT1PNP | |
| SCHEMBL2734697 | 0.75 | POLB (0.77) | POLBPOLA1POLGHPRT1PNP | |
| SCHEMBL18640684 | 0.75 | POLB (0.49) | POLBPOLA1POLGHPRT1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105246902-A | Acyclic nucleoside phosphonate diesters | UNIV CALIFORNIA | 2016-01-13 | — | — | CN | disclosed |