Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.84 |
| ▸ | MAPT | P10636 | 6/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.84 |
| ▸ | GAA | P10253 | 2/20 | 0.84 |
| ▸ | RAB9A | P51151 | 7/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | AHR | P35869 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | KDR | P35968 | 2/20 | 0.63 |
| ▸ | DHODH | Q02127 | 4/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075528 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL12431830 | 0.84 | DHODH (0.77) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL18979213 | 0.84 | MEN1 (0.78) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL15528907 | 0.84 | MEN1 (0.78) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL12561360 | 0.83 | MEN1 (0.68) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL16007507 | 0.83 | KDR (0.88) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL16625628 | 0.82 | KDR (0.84) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL16017736 | 0.81 | KDR (0.70) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL14368225 | 0.81 | KDM4E (0.64) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL846930 | 0.81 | DHODH (0.76) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099758-A1 | Alpha 7 Nicotinic Acetylcholine Receptor Allosteric Modulators, Their Derivatives and Uses Thereof | ANVYL LLC (US) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099758-A1 | Alpha 7 Nicotinic Acetylcholine Receptor Allosteric Modulators, Their Derivatives and Uses Thereof | CHRNA7, CHRNA1, CHRNA2 | MEN1 4409/4885KMT2A 2959/4885MAPT 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.