Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.84 |
| ▸ | MAPT | P10636 | 8/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | HTT | P42858 | 2/20 | 0.84 |
| ▸ | GLA | P06280 | 1/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.79 |
| ▸ | GAA | P10253 | 3/20 | 0.79 |
| ▸ | KDR | P35968 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18979206 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL15528988 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL18979185 | 0.89 | MEN1 (0.86) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL15529196 | 0.89 | MEN1 (0.86) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL15528578 | 0.88 | MEN1 (0.84) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL18979215 | 0.88 | MEN1 (0.84) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL16625628 | 0.88 | KDR (0.84) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL15529069 | 0.87 | KMT2A (0.82) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL16625606 | 0.85 | KDR (0.69) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL16625600 | 0.80 | MEN1 (0.84) | MEN1KMT2AMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099758-A1 | Alpha 7 Nicotinic Acetylcholine Receptor Allosteric Modulators, Their Derivatives and Uses Thereof | ANVYL LLC (US) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099758-A1 | Alpha 7 Nicotinic Acetylcholine Receptor Allosteric Modulators, Their Derivatives and Uses Thereof | CHRNA7, CHRNA1, CHRNA2 | MEN1 4409/4885KMT2A 2959/4885MAPT 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.