Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608711 | 0.87 | TP53 (0.43) | TP53PARP1TOP2AG6PDMPO | |
| SCHEMBL30721748 | 0.87 | TP53 (0.43) | TP53PARP1TOP2AG6PDMPO | |
| Hydrochloric Acid SCHEMBL14472088 | 0.85 | TP53 (0.42) | TP53PARP1TOP2AG6PDMPO | |
| SCHEMBL16627377 | 0.85 | POLB (0.36) | TP53PARP1TOP2AG6PDMPO | |
| SCHEMBL16625686 | 0.84 | TOP2A (0.33) | PARP1TOP2AG6PDTSHRMPO | |
| SCHEMBL16625680 | 0.84 | CYP1A2 (0.34) | PARP1TOP2AG6PDTSHRMPO | |
| SCHEMBL16625682 | 0.84 | TOP2A (0.37) | TP53PARP1TOP2AG6PDTSHR | |
| SCHEMBL16625690 | 0.84 | TP53 (0.39) | TP53PARP1TOP2AG6PDTSHR | |
| SCHEMBL12608688 | 0.80 | TP53 (0.39) | TP53PARP1TOP2AG6PDMPO | |
| SCHEMBL16454745 | 0.79 | G6PD (0.51) | TP53PARP1TOP2AG6PDMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050471-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |