Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.31 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625656 | 0.84 | TP53 (0.40) | TOP2AG6PDTSHRMPOPARP1 | |
| SCHEMBL14548880 | 0.80 | G6PD (0.50) | TOP2AG6PDMPOPARP1SLC6A4 | |
| SCHEMBL16625657 | 0.80 | TP53 (0.38) | TOP2AG6PDMPOPARP1SLC6A4 | |
| SCHEMBL16625975 | 0.78 | SIGMAR1 (0.34) | TOP2AG6PDTSHRPARP1SLC6A4 | |
| SCHEMBL16625683 | 0.78 | PARP1 (0.35) | TOP2AG6PDMPOPARP1CYP1A2 | |
| SCHEMBL16625680 | 0.77 | CYP1A2 (0.34) | TOP2AG6PDTSHRMPOPARP1 | |
| SCHEMBL16454260 | 0.76 | TP53 (0.47) | G6PDWEE1KMT2AL3MBTL1MEN1 | |
| SCHEMBL16454376 | 0.76 | TSHR (0.33) | G6PDTSHRPARP1TNKS2PARP2 | |
| SCHEMBL16625979 | 0.75 | PARP1 (0.33) | G6PDPARP1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16625976 | 0.74 | SIGMAR1 (0.36) | TOP2AG6PDTSHRMPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050471-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |