SCHEMBL16625722

SCHEMBL16625722

Cc1cnc2c(c1)c1ccccc1n2C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.50
MEN1 O00255 1/20 0.46
NR1I2 O75469 1/20 0.46
AHR P35869 1/20 0.46
KMT2A Q03164 1/20 0.46
PTGER4 P35408 2/20 0.46
PDE10A Q9Y233 10/20 0.45
ALKBH5 Q6P6C2 1/20 0.43
FTO Q9C0B1 1/20 0.43
TOP2A P11388 1/20 0.43
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 1/20 0.42
NQO2 P16083 1/20 0.42
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678729 0.81 PDE10A (0.50) GPR3MEN1KMT2APTGER4PDE10A
SCHEMBL14418729 0.80 PTGER4 (0.69) MEN1KMT2APTGER4LMNAL3MBTL1
SCHEMBL16621646 0.80 PTGER4 (0.43) GPR3MEN1KMT2APTGER4ALKBH5
SCHEMBL22373828 0.79 KDM4E (0.52) MEN1KMT2APTGER4PDE10AL3MBTL1
SCHEMBL25635426 0.77 PTGER4 (0.40) MEN1NR1I2AHRKMT2APTGER4
SCHEMBL678784 0.76 GRM5 (0.55) GPR3MEN1KMT2APTGER4PDE10A
SCHEMBL19055783 0.76 PTGER4 (0.41) GPR3MEN1KMT2APTGER4PDE10A
SCHEMBL17109982 0.76 GABRP (0.55) GPR3MEN1NR1I2AHRKMT2A
SCHEMBL19050736 0.74 PTGER4 (0.45) MEN1KMT2APTGER4PDE10ALMNA
SCHEMBL280139 0.74 GPR3 (0.58) GPR3PDE10AALKBH5FTOLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072270-A1 PROTAC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF 百极弘烨(南通)医药科技有限公司 2023-05-04 WO disclosed
US-9941422-B2 Organic photoelectric conversion element and solar cell using the same Konica Minolta, Inc. (JP) 2018-04-10 US disclosed
US-9941422-B2 Organic photoelectric conversion element and solar cell using the same Konica Minolta, Inc. (JP) 2018-04-10 US disclosed
US-9882072-B2 Solar cell and transparent electrode Konica Minolta, Inc. (JP) 2018-01-30 US disclosed
US-9882072-B2 Solar cell and transparent electrode Konica Minolta, Inc. (JP) 2018-01-30 US disclosed
US-20150221793-A1 SOLAR CELL AND TRANSPARENT ELECTRODE Konica Minolta, Inc. (JP) 2015-08-06 US disclosed
US-20150096610-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL USING THE SAME SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2015-04-09 US disclosed
US-20150096610-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL USING THE SAME SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2015-04-09 US disclosed