Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663111 | 0.80 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1MAPTCASP1 | |
| SCHEMBL1663127 | 0.78 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1MAPTCASP1 | |
| SCHEMBL1663018 | 0.78 | CASP1 (0.49) | KDM4EHSD17B10ALDH1A1MAPTCASP1 | |
| SCHEMBL1662820 | 0.76 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1MAPTCASP1 | |
| SCHEMBL3694603 | 0.75 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1MAPTCASP1 | |
| SCHEMBL1662585 | 0.74 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1MAPTCASP1 | |
| SCHEMBL3691646 | 0.74 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1MAPTCASP1 | |
| SCHEMBL21355438 | 0.73 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1MAPTCASP1 | |
| SCHEMBL1663187 | 0.73 | MAPT (0.40) | KDM4EHSD17B10ALDH1A1MAPTCASP1 | |
| SCHEMBL1663210 | 0.72 | MAPT (0.44) | KDM4EHSD17B10ALDH1A1MAPTCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |