Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663111 | 0.83 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1TTRAPOBEC3A | |
| SCHEMBL3694603 | 0.78 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1TTRAPOBEC3A | |
| SCHEMBL1662574 | 0.78 | KDM4E (0.45) | KDM4EHSD17B10ALDH1A1TTRAPOBEC3A | |
| SCHEMBL1663018 | 0.78 | CASP1 (0.49) | KDM4EHSD17B10ALDH1A1TTRAPOBEC3A | |
| SCHEMBL1662585 | 0.77 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1TTRAPOBEC3A | |
| SCHEMBL3691646 | 0.77 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1TTRAPOBEC3A | |
| SCHEMBL3687213 | 0.76 | GRIN2D (0.38) | KDM4EALDH1A1TTRAPOBEC3ASMN1; SMN2 | |
| SCHEMBL1662820 | 0.76 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1TTRAPOBEC3A | |
| SCHEMBL21355438 | 0.76 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1TTRAPOBEC3A | |
| SCHEMBL23905480 | 0.73 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1APOBEC3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |