SCHEMBL16625787

SCHEMBL16625787

Cc1ccc2c(c1)c1ncccc1n2-c1cccc(-n2c3ccc(C)cc3c3ncccc32)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
NR1I2 O75469 1/20 0.41
AHR P35869 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
NPC1 O15118 2/20 0.40
HSP90AA1 P07900 2/20 0.40
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
HTT P42858 2/20 0.38
LMNA P02545 2/20 0.38
HPGD P15428 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CCR1 P32246 1/20 0.37
CCR8 P51685 1/20 0.37
FGFR1 P11362 1/20 0.37
MAPK1 P28482 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1609866 0.91 KDM4E (0.44) MEN1KMT2ANR1I2AHRL3MBTL1
SCHEMBL1611068 0.87 CYP1A2 (0.46) MEN1KMT2ANR1I2AHRL3MBTL1
SCHEMBL18101994 0.86 PDE4A (0.39) MEN1KMT2ANR1I2AHRL3MBTL1
SCHEMBL17348485 0.85 MEN1 (0.39) MEN1KMT2ANR1I2AHRKDM4E
SCHEMBL5944436 0.83 MEN1 (0.35) MEN1KMT2ANR1I2AHRL3MBTL1
SCHEMBL261961 0.83 KDM4E (0.47) MEN1KMT2ANR1I2L3MBTL1NPC1
SCHEMBL16625767 0.82 HTT (0.36) MEN1KMT2AL3MBTL1NPC1HSP90AA1
SCHEMBL19862095 0.81 ALDH1A1 (0.40) MEN1KMT2ANR1I2AHRL3MBTL1
SCHEMBL5944419 0.81 MEN1 (0.38) MEN1KMT2ANR1I2AHRL3MBTL1
SCHEMBL8282722 0.81 MEN1 (0.41) MEN1KMT2ANR1I2AHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9941422-B2 Organic photoelectric conversion element and solar cell using the same Konica Minolta, Inc. (JP) 2018-04-10 US disclosed
US-9818962-B2 Organic electroluminescent element and method for manufacturing same Konica Minolta, Inc. (JP) 2017-11-14 US disclosed
US-20170110677-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME MERCK PATENT GMBH (DE) 2017-04-20 US disclosed
US-20170005295-A1 LIGHT EXTRACTION LAYERED BODY, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND METHOD FOR MANUFACTURING SAME Konica Minolta, Inc. (JP) 2017-01-05 US disclosed
US-20160380227-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2016-12-29 US disclosed
US-20160285008-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE Konica Minolta, Inc. (JP) 2016-09-29 US disclosed
US-20160111676-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2016-04-21 US disclosed
US-20150207080-A1 TRANSPARENT ELECTRODE, ELECTRONIC DEVICE, AND METHOD FOR MANUFACTURING TRANSPARENT ELECTRODE KONICA MINOLTA INC. (JP) 2015-07-23 US disclosed
US-20150096610-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL USING THE SAME SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2015-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160285008-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE EML4, L1CAM, OCIAD2 MEN1 3335/4885KMT2A 2809/4885NR1I2 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.