Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13777455 | 1.00 | HCAR2 (0.45) | HCAR2LMNATHRBNPC1RAB9A | |
| SCHEMBL16625920 | 1.00 | HCAR2 (0.45) | HCAR2LMNATHRBNPC1RAB9A | |
| SCHEMBL12534114 | 1.00 | HCAR2 (0.45) | HCAR2LMNATHRBNPC1RAB9A | |
| SCHEMBL9915733 | 0.99 | HCAR2 (0.44) | HCAR2LMNATHRBNPC1RAB9A | |
| SCHEMBL13778858 | 0.97 | HCAR2 (0.45) | HCAR2LMNATHRBNPC1RAB9A | |
| SCHEMBL172480 | 0.97 | HCAR2 (0.45) | HCAR2LMNATHRBNPC1RAB9A | |
| SCHEMBL2602487 | 0.96 | HCAR2 (0.49) | HCAR2LMNATHRBALDH1A1AKR1B10 | |
| SCHEMBL2602451 | 0.96 | HCAR2 (0.49) | HCAR2LMNATHRBALDH1A1AKR1B10 | |
| SCHEMBL12255590 | 0.94 | THRB (0.41) | HCAR2LMNATHRBNPC1RAB9A | |
| SCHEMBL12727904 | 0.94 | MMP12 (0.43) | HCAR2LMNATHRBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9500967-B2 | Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20150099218-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2015-04-09 | — | — | US | disclosed |