SCHEMBL16626401

SCHEMBL16626401

CNCc1cn([S+]([O-])c2cccnc2)c2cc(Nc3ccc(Cl)cc3C)ccc12

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 7/20 0.37
SLC6A4 P31645 7/20 0.37
NAMPT P43490 2/20 0.32
CYP11B2 P19099 2/20 0.32
GAA P10253 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MAT2A P31153 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
P2RX7 Q99572 1/20 0.30
CYP11B1 P15538 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19984004 0.91 MEN1 (0.32) NAMPTALDH1A1HPGDSMN1; SMN2
SCHEMBL16626453 0.87
SCHEMBL16626370 0.87 MAPK8 (0.35) NAMPTALDH1A1RAB9ASMN1; SMN2
SCHEMBL19984214 0.87 MEN1 (0.32) SLC6A2SLC6A4NAMPTALDH1A1
SCHEMBL16626476 0.86
SCHEMBL16626457 0.86 PARP14 (0.33)
SCHEMBL19984086 0.85 EGFR (0.34) SLC6A2SLC6A4
SCHEMBL16626484 0.85 BCL6 (0.36)
SCHEMBL16626477 0.85
SCHEMBL19983730 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015050412-A1 SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2015-04-09 WO disclosed