⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983811 | 0.92 | — | — | |
| SCHEMBL16626476 | 0.91 | — | — | |
| SCHEMBL19983881 | 0.89 | — | — | |
| SCHEMBL16626457 | 0.88 | PARP14 (0.33) | — | |
| SCHEMBL16626424 | 0.87 | MAPK14 (0.36) | — | |
| SCHEMBL19984004 | 0.86 | MEN1 (0.32) | — | |
| SCHEMBL16626468 | 0.86 | METAP2 (0.30) | — | |
| SCHEMBL19984151 | 0.86 | — | — | |
| SCHEMBL16626693 | 0.85 | TBXAS1 (0.31) | — | |
| SCHEMBL19984136 | 0.85 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |