Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MAP3K8 | P41279 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984214 | 0.91 | MEN1 (0.32) | EGFRSLC6A2SLC6A4HTR2C | |
| SCHEMBL16626370 | 0.88 | MAPK8 (0.35) | HTR2CMAPK14 | |
| SCHEMBL16626715 | 0.87 | GRM4 (0.33) | EGFRHTR2C | |
| SCHEMBL16626433 | 0.86 | EGFR (0.33) | EGFRMAP3K8MAPK13EIF2AK2MAPK12 | |
| SCHEMBL16626499 | 0.86 | DOT1L (0.31) | EGFR | |
| SCHEMBL19984136 | 0.85 | MEN1 (0.39) | EGFRHTR2C | |
| SCHEMBL16626401 | 0.85 | SLC6A2 (0.37) | SLC6A2SLC6A4 | |
| SCHEMBL19983986 | 0.85 | ALDH1A1 (0.31) | EGFR | |
| SCHEMBL16626694 | 0.84 | — | — | |
| SCHEMBL19983730 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |