SCHEMBL16626461

SCHEMBL16626461

CNCc1cn([S+]([O-])c2cccnc2)c2cc(Nc3ccnc(Cl)c3Br)ccc12

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCL6 P41182 19/20 0.33
DOT1L Q8TEK3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16626484 0.92 BCL6 (0.36) BCL6
SCHEMBL16626707 0.89 PTK6 (0.30)
SCHEMBL16626499 0.86 DOT1L (0.31) DOT1L
SCHEMBL16626370 0.85 MAPK8 (0.35) BCL6
SCHEMBL16626457 0.85 PARP14 (0.33)
SCHEMBL16626453 0.84
SCHEMBL19984214 0.84 MEN1 (0.32)
SCHEMBL16626401 0.83 SLC6A2 (0.37)
SCHEMBL16626468 0.83 METAP2 (0.30)
SCHEMBL16626715 0.83 GRM4 (0.33) BCL6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015050412-A1 SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2015-04-09 WO disclosed