Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626476 | 0.91 | — | — | |
| SCHEMBL16626464 | 0.89 | NAMPT (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19983881 | 0.89 | — | — | |
| SCHEMBL19984151 | 0.87 | — | — | |
| SCHEMBL16626707 | 0.85 | PTK6 (0.30) | — | |
| SCHEMBL16626477 | 0.84 | — | — | |
| SCHEMBL19984004 | 0.84 | MEN1 (0.32) | — | |
| SCHEMBL16626457 | 0.84 | PARP14 (0.33) | — | |
| SCHEMBL16626401 | 0.83 | SLC6A2 (0.37) | — | |
| SCHEMBL16626424 | 0.82 | MAPK14 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |