Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12230156 | 0.72 | TSHR (0.37) | HTR2AHTR2BKCNH2TDP1MEN1 | |
| SCHEMBL6829825 | 0.72 | TDP1 (0.49) | HTR2AHTR2BKCNH2TDP1MEN1 | |
| SCHEMBL2208990 | 0.68 | KDM4E (0.43) | TDP1MEN1KMT2ATSHRPOLB | |
| SCHEMBL23732865 | 0.68 | NOS2 (0.41) | KCNH2TSHRKDM4E | |
| SCHEMBL8047204 | 0.67 | RAB9A (0.48) | HTR2AHTR2BTDP1MEN1KMT2A | |
| SCHEMBL358474 | 0.67 | MEN1 (0.59) | KCNH2TDP1MEN1KMT2ALMNA | |
| SCHEMBL9407115 | 0.67 | TDP1 (0.45) | HTR2AHTR2BKCNH2TDP1MEN1 | |
| SCHEMBL1243824 | 0.67 | KCNA5 (0.47) | MEN1KMT2AACHECA12CA1 | |
| SCHEMBL31482560 | 0.67 | KCNA5 (0.47) | MEN1KMT2AACHECA12CA1 | |
| SCHEMBL13459312 | 0.67 | KDM4E (0.41) | HTR2AHTR2BTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235911-A2 | INHIBIN SUBUNIT BETA E-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2025-11-13 | — | — | WO | disclosed |
| US-20220220134-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2022-07-14 | — | — | US | disclosed |
| US-10351581-B2 | Phosphohistidine mimetics and antibodies to same | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-07-16 | — | — | US | disclosed |
| US-20190092796-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-03-28 | — | — | US | disclosed |
| US-20160311838-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY | 2016-10-27 | — | — | US | disclosed |
| WO-2015051079-A2 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092796-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | PHPT1, CD4, CD81 | HTR2A 4074/4885HTR2B 4082/4885KCNH2 4643/4885 |
| US-20160311838-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | PHPT1, CD4, HCLS1 | HTR2A 3773/4885HTR2B 3746/4885KCNH2 4338/4885 |
| US-20220220134-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | PHPT1, CD4, CD81 | HTR2A 4074/4885HTR2B 4082/4885KCNH2 4643/4885 |
| US-10351581-B2 | Phosphohistidine mimetics and antibodies to same | PHPT1, CD4, HCLS1 | HTR2A 3773/4885HTR2B 3746/4885KCNH2 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.