Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17954325 | 0.91 | FFAR1 (0.47) | FFAR1BCHEPPARDAKR1B1FFAR4 | |
| SCHEMBL16624616 | 0.84 | FFAR1 (0.49) | FFAR1PPARDAKR1B1FFAR4ANO1 | |
| SCHEMBL20101406 | 0.83 | FFAR1 (0.41) | FFAR1BCHEPPARDMAOB | |
| SCHEMBL16631068 | 0.81 | MAOB (0.47) | FFAR1BCHEPPARDMAOBANO1 | |
| SCHEMBL17954312 | 0.78 | FFAR1 (0.48) | FFAR1BCHEPPARDMAOBANO1 | |
| SCHEMBL16627143 | 0.78 | FFAR1 (0.41) | FFAR1PPARDAKR1B1FFAR4ANO1 | |
| SCHEMBL12847632 | 0.77 | LTA4H (0.49) | — | |
| SCHEMBL12847916 | 0.77 | LTA4H (0.49) | — | |
| SCHEMBL16624618 | 0.76 | FFAR1 (0.48) | FFAR1PPARDAKR1B1FFAR4ANO1 | |
| SCHEMBL9405631 | 0.75 | MAOB (0.71) | FFAR1BCHEPPARDMAOBANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051044-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |