Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1185533 | 0.82 | MAPT (0.51) | MAPTHPGDNPSR1LMNAALDH1A1 | |
| SCHEMBL16624687 | 0.78 | ALDH1A1 (0.55) | MAPTHPGDLMNAALDH1A1HTT | |
| SCHEMBL14930228 | 0.75 | KMT2A (0.55) | MAPTHPGDNPSR1LMNAALDH1A1 | |
| SCHEMBL28329030 | 0.72 | ALDH1A1 (0.58) | MAPTHPGDALDH1A1HTTPOLB | |
| SCHEMBL17183180 | 0.70 | MAPT (0.48) | MAPTLMNAALDH1A1TSHRPOLB | |
| SCHEMBL16624696 | 0.70 | TP53 (0.54) | MAPTLMNATSHRMEN1POLB | |
| SCHEMBL16046762 | 0.69 | MTNR1B (0.66) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1185546 | 0.69 | MEN1 (0.53) | MAPTHPGDLMNAALDH1A1HTT | |
| SCHEMBL31146171 | 0.69 | POLB (0.53) | MAPTHPGDLMNAALDH1A1POLB | |
| SCHEMBL1186093 | 0.69 | MAPT (0.51) | MAPTHPGDLMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051044-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |