Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624801 | 0.91 | FFAR1 (0.47) | FFAR1CYP4F2CYP4A11FFAR4AKR1B1 | |
| SCHEMBL16624625 | 0.90 | FFAR1 (0.47) | FFAR1CYP4F2CYP4A11FFAR4AKR1B1 | |
| SCHEMBL16624848 | 0.87 | DGAT1 (0.41) | FFAR1FFAR4CASP3SENP8SENP7 | |
| SCHEMBL18027825 | 0.85 | FFAR1 (0.48) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL16631081 | 0.84 | FFAR1 (0.43) | FFAR1CYP4F2CYP4A11CASP3SENP8 | |
| SCHEMBL17954319 | 0.83 | FFAR1 (0.47) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL16624623 | 0.83 | FFAR1 (0.52) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL16624844 | 0.83 | FFAR1 (0.48) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL16624843 | 0.82 | FFAR1 (0.47) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL20101406 | 0.79 | FFAR1 (0.41) | FFAR1CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051044-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |